San Francisco 49ers running back Isaac Guerendo has been diagnosed with a sprained foot, head coach Kyle Shanahan announced on Monday.
The 24-year-old running back left Sunday's 38-13 victory over the Chicago Bears with just over five minutes remaining in regulation. He recorded 15 carries for 78 yards and two catches for 50 yards before his exit.
Guerendo has recorded 246 yards this season with two touchdowns and three fumbles in his rookie season.
With both Christian McCaffrey and Jordan Mason on the injured reserve list, it looks like the 49ers may need to dig even deeper into their depth chart. Next in line will be 26-year-old Patrick Taylor Jr., who recorded 25 yards on seven carries with one touchdown in Sunday's victory.
The best-case scenario for the 49ers would be a quick turnaround for the young running back. However, with the team's next game coming on Thursday night against the Los Angeles Rams, he will have limited time to try to get back on the field.
The 49ers have been riddled with injuries this season. On Sunday alone, they had nine players listed as out or questionable.
San Francisco currently sits tied for last place with the Arizona Cardinals in the NFC West.
